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Intravenous Vitamin C and CancerQuackery or a Valid Medical Therapy For Malignant Tumors?
A popular oral supplement especially for colds and flu, vitamin C has also been used intravenously. Is there a scientific basis to this controversial therapy?
The recommended daily intake (RDA) for vitamin C (ascorbic acid) is 60 mg. This is enough to prevent scurvy, but there has long been a debate about whether larger doses can be helpful. Humans are, after all, among the rare mammals who cannot produce their own vitamin C. It has been suggested that if we did, our production would amount to several grams a day. Many people take large doses of the vitamin when they catch a cold, though not all studies have shown any benefit to this practice. Proponents of the vitamin have criticized those studies for using too low doses. We do know that vitamin C is safe even in very large amounts, although it can cause stomach upset and diarrhea. This may be lessened by taking a buffered (salt) form, such as calcium ascorbate. Route of AdministrationThe problem is that the human body limits the amount of vitamin C absorbed orally. The more you take, the less of it gets absorbed - the "expensive pee" argument against vitamin supplementation. Intravenous therapy with vitamin C has been used to overcome the obstacle of limited oral absorption. In 1971 Doctor Frederick R. Klenner published a paper about the use of massive doses of I.V. ascorbate, up to 150 grams, to treat a variety of conditions, such as infections caused by enteroviruses (including polioviruses) and herpesviruses (like mononucleosis and chicken pox), arthritis, viral hepatitis, burns, insect and snake bites and severe allergic reactions. He reported that it "also eliminates pain [from burns]." Vitamin C for CancerKlenner was also an advocate of using intravenous vitamin C for cancer, which has later become the main use of this therapy. For a long time it has been scoffed at as quackery, with studies finding little or no benefit - but most of these studies were done using oral vitamin C. In contrast, a recent study conducted by the National Institutes of Health (NIH) found that high concentrations of vitamin C (achieved by I.V. doses similar to those used by Klenner) had anticancer effects in 75 percent of the tested cancer cell lines. Non-cancerous cells were unaffected. Tumor weight was reduced by 41-53 percent in animals with advanced cancer. The FutureEven if these findings are confirmed in humans, it could take a while before vitamin C becomes accepted as a cancer therapy. It may not be the cure for cancer, but it might prolong the lives of those who have not benefited from other therapy. As a cancer treatment, vitamin C has the benefits of being safe and relatively inexpensive. And even if it does not offer a cure, it can improve the quality of the remaining days. A study conducted on terminal cancer patients found that I.V. ascorbate significantly improved fatigue, cognitive function, pain and even emotional status. As a word of caution, it is far too early to recommend ditching chemotherapy and other medications in favour of the vitamin. Those undergoing conventional cancer therapy should not take vitamin C without their doctor's approval, as it could actually reduce the efficacy of some treatments. It is interesting that in Japan intravenous vitamin C is widely used for many conditions, such as pneumonia, allergies and autoimmune diseases. Perhaps in the future the Western world will follow suite. Only time will tell. ReferencesKlenner FR. Observations On the Dose and Administration of Ascorbic Acid When Employed Beyond the Range Of A Vitamin In Human Pathology. J Appl Nutr. 1971;23(3/4):61-88. Yeom CH, Jung GC, Song KJ. Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration. J Korean Med Sci. 2007 Feb;22(1):7-11. NIH News: Vitamin C Injections Slow Tumor Growth in Mice See AlsoThe Promise of Low Dose Naltrexone Therapy Treatments for Pancreatic Cancer Benefits and Properties of Chaga Mushroom
The copyright of the article Intravenous Vitamin C and Cancer in Alternative Cancer Treatments is owned by Maija Haavisto. Permission to republish Intravenous Vitamin C and Cancer in print or online must be granted by the author in writing.
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